With her background in Health Sciences and Epidemiology and her drive as an entrepreneur, Karen participated in a number of companies in The Netherlands and other European countries and led them to growth. She was one of the founders of DOCS International. Within 8 years the company had grown to a full service global staffing organisation for the Pharma, Biotech and Medical Devices industries. When DOCS was acquired by the listed company ICON Plc Karen continued on at the company as the Group Director Central Services. In 2011 she was one of the three founding partners of Van der Laan & Company, an executive search firm with a strong focus on diversity. In 2021 Van der Laan & Company and Partners at Worked merged and Karen is now one of the leading partners.
In addition Karen is a mentor to various start-up companies, advisor and jury member at Utrecht Inc and non-executive Board Member of a new assisted living concept for elderly people with dementia. Karen is a certified mediator and qualified partner in Talent Motivational Analyses for (non)executive board members and teams.